Pet Recall Facts

Ingredients / Praziquantel

Praziquantel: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

84,265Total reports
62,721Dog reports
12,245Cat reports

FDA-approved products with this ingredient (Green Book)

All approved products with this ingredient, for any species.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

19873
19883
19892
19904
19915
19929
199316
199417
199521
199651
199754
199862
199952
200044
200159
200288
2003256
2004350
2005321
2006352
2007702
20081,033
20091,253
20101,573
20111,586
20121,958
20132,810
20143,373
20153,249
20163,853
20175,681
20186,628
20197,466
20207,138
20216,109
20225,018
20235,618
20246,639
20257,097
20263,710

Species named in reports

Dog62,721
Cat12,245
Not given5,941
Horse2,969
Human318
Donkey26
Other8
Goat6

Signs reported after Praziquantel

Vomiting17,861
Lack of efficacy (endoparasite) - heartworm10,108
Lethargy (see also Central nervous system depression in Neurological)7,146
Diarrhoea6,543
Lack of efficacy (endoparasite) - hookworm4,894
INEFFECTIVE, HOOKS3,145
Lack of efficacy (endoparasite) - tapeworm2,971
Hypersalivation2,474
Other abnormal test result NOS2,386
Ataxia2,361
UNPALATABLE2,358
Behavioural disorder NOS2,270
Anorexia2,227
Lack of efficacy (endoparasite) - roundworm NOS2,166
INEFFECTIVE, HEARTWORM LARVAE2,163
Emesis (multiple)1,946
Not eating1,883
Seizure NOS1,766
Emesis1,756
Death1,600
Application site alopecia1,511
Lack of efficacy - NOS1,408
Lack of efficacy (roundworm)1,308
Overdose1,156
Decreased appetite1,141

Breeds named in reports

Retriever - Labrador8,625
Dog (unknown)7,505
Domestic Shorthair6,872
Crossbred Canine/dog6,702
Retriever - Golden3,285
Shepherd Dog - German3,047
Chihuahua2,395
Pit Bull2,236
Poodle (unspecified)2,096
Beagle1,821
Shih Tzu1,777
Terrier - Yorkshire1,764
Cat (unknown)1,752
Shepherd Dog - Australian1,741
Boxer (German Boxer)1,332

Reported outcomes

Outcome Unknown37,624
Recovered/Normal22,745
Ongoing9,272
Died1,839
Euthanized843
Recovered with Sequela250

Report a problem to FDA