Pet Recall Facts

Ingredients / Methylprednisolone Acetate

Methylprednisolone Acetate: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

2,294Total reports
551Dog reports
1,466Cat reports

FDA-approved products with this ingredient (Green Book)

All approved products with this ingredient, for any species.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

19876
19888
19893
19907
199111
199212
19938
19947
19958
19967
19976
199815
19997
20006
200113
200221
200334
200451
200539
200652
200749
200870
200980
2010103
201189
201299
2013110
2014120
2015154
2016140
201794
201872
2019109
202088
202178
202260
202397
2024143
2025156
202662

Species named in reports

Cat1,466
Dog551
Not given162
Horse102
Other5
Human3
Pig1
Sheep1

Signs reported after Methylprednisolone Acetate

Lethargy (see also Central nervous system depression in Neurological)292
Vomiting287
Anorexia254
Death232
Lack of efficacy - NOS198
Weight loss171
Death by euthanasia161
Hyperglycaemia142
INEFFECTIVE, ANTIINFLAMMATORY138
Ataxia128
Depression128
Other abnormal test result NOS124
Elevated alanine aminotransferase (ALT)115
Diarrhoea110
Fever108
Abnormal radiograph finding97
Dyspnoea94
Polydipsia91
Anaemia NOS90
Behavioural disorder NOS86
Elevated blood urea nitrogen (BUN)84
Not eating78
Suspension, Abnormal74
Leucocytosis NOS73
Pruritus73

Breeds named in reports

Domestic Shorthair692
Domestic (unspecified)338
Dog (unknown)79
Cat (unknown)79
Cat (other)76
Domestic Longhair75
Domestic Mediumhair58
Retriever - Labrador51
Quarter Horse40
Siamese39
Crossbred Canine/dog37
Terrier - Yorkshire33
Horse (unknown)23
Poodle (unspecified)22
Retriever - Golden22

Reported outcomes

Ongoing708
Died298
Outcome Unknown258
Recovered/Normal213
Euthanized116
Recovered with Sequela4

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