Pet Recall Facts

Ingredients / Melarsomine

Melarsomine: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

23,871Total reports
22,672Dog reports
8Cat reports

FDA-approved products with this ingredient (Green Book)

All approved products with this ingredient, for any species.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

19953
1996321
1997111
1998167
1999199
2000178
2001262
2002300
2003451
2004793
2005691
2006871
2007846
2008962
20091,076
20101,161
2011994
20121,157
2013986
20141,011
20151,060
20161,219
20171,205
20181,155
20191,047
20201,120
20211,045
2022964
2023681
2024778
2025707
2026348

Species named in reports

Dog22,672
Not given1,062
Human104
Other24
Cat8
Other Canids1

Signs reported after Melarsomine

INEFFECTIVE, HEARTWORM ADULTS4,219
Lack of efficacy (endoparasite) - heartworm2,801
Vomiting2,728
Injection site swelling2,300
Injection site pain1,480
Lethargy (see also Central nervous system depression in Neurological)1,332
Pain NOS1,285
Anorexia1,220
Diarrhoea1,187
INEFFECTIVE, HEARTWORM LARVAE1,121
Depression1,095
Fever998
Death958
Elevated alanine aminotransferase (ALT)941
Cough935
Injection site lump925
Hypersalivation895
Panting838
Polypnoea676
Bloody diarrhoea651
Lack of efficacy - NOS617
Cardiac disorder NOS588
Ataxia558
Restlessness534
Vials, Damaged524

Breeds named in reports

Crossbred Canine/dog3,898
Retriever - Labrador3,205
Dog (unknown)2,290
Shepherd Dog - German1,299
Beagle1,003
Pit Bull811
Boxer (German Boxer)763
Chihuahua758
Retriever - Golden720
Dog (other)597
Rottweiler548
Terrier - Bull - American Pit528
Dachshund (unspecified)406
Terrier (unspecified)359
Siberian Husky334

Reported outcomes

Outcome Unknown6,077
Ongoing5,300
Recovered/Normal1,712
Died1,134
Recovered with Sequela724
Euthanized182

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