Pet Recall Facts

Ingredients / Lufenuron

Lufenuron: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

39,638Total reports
36,510Dog reports
1,149Cat reports

FDA-approved products with this ingredient (Green Book)

All approved products with this ingredient, for any species.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

1995227
1996432
1997123
1998270
1999499
2000409
2001255
2002194
2003224
2004531
2005552
2006749
2007971
20081,125
20091,256
20101,195
20111,242
20121,067
20131,274
20142,931
20153,122
20163,255
20173,173
20182,803
20192,556
20202,172
20211,575
20221,365
20231,211
20241,242
20251,180
2026458

Species named in reports

Dog36,510
Not given1,857
Cat1,149
Human108
Ferret3
Other3
Goat2
Other Canids2

Signs reported after Lufenuron

INEFFECTIVE, HEARTWORM LARVAE5,696
Vomiting5,608
Lack of efficacy (endoparasite) - hookworm4,280
Lack of efficacy (endoparasite) - heartworm3,537
Diarrhoea3,121
Lethargy (see also Central nervous system depression in Neurological)2,070
INEFFECTIVE, ASCARIDS NOS1,999
INEFFECTIVE, HOOKS1,845
Lack of efficacy - NOS1,363
Depression1,344
Lack of efficacy (endoparasite) - whipworm1,333
Lack of efficacy (ectoparasite) - flea1,299
Anorexia1,283
Pruritus1,048
Emesis934
Lack of efficacy (endoparasite) - roundworm NOS867
Seizure NOS786
Emesis (multiple)703
Ataxia664
Underfilling, Package663
Lack of efficacy (endoparasite) - tapeworm553
Bloody diarrhoea543
Product problem528
Drug dose omission509
Overdose497

Breeds named in reports

Crossbred Canine/dog5,917
Retriever - Labrador4,988
Dog (unknown)1,928
Retriever - Golden1,794
Shepherd Dog - German1,665
Beagle1,106
Chihuahua1,019
Terrier - Yorkshire957
Shih Tzu863
Boxer (German Boxer)842
Pit Bull808
Dachshund (unspecified)754
Shepherd Dog - Australian724
Domestic (unspecified)687
Poodle (unspecified)589

Reported outcomes

Outcome Unknown11,606
Recovered/Normal8,337
Ongoing7,472
Died642
Euthanized237
Recovered with Sequela169

Report a problem to FDA