Pet Recall Facts

Ingredients / Lotilaner

Lotilaner: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

14,818Total reports
12,739Dog reports
903Cat reports

FDA-approved products with this ingredient (Green Book)

All approved products with this ingredient, for any species.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

20152
20172
2018574
20191,303
20201,810
20211,446
20221,321
20231,455
20241,586
20253,144
20262,175

Species named in reports

Dog12,739
Not given1,144
Cat903
Human29
Pig1
Cattle1
Rabbit1

Signs reported after Lotilaner

Vomiting3,663
Diarrhoea1,774
Lethargy (see also Central nervous system depression in Neurological)1,490
UNPALATABLE1,064
Other abnormal test result NOS952
Lack of efficacy (ectoparasite) - tick NOS814
Seizure NOS797
Lack of efficacy (bacteria) - Borrelia788
Behavioural disorder NOS677
Lack of efficacy (ectoparasite) - flea669
Lack of efficacy (endoparasite) - heartworm587
Not eating555
Lack of efficacy (endoparasite) - hookworm385
Emesis (multiple)352
Itching347
Ataxia333
Decreased appetite317
Panting280
Shaking267
Lack of efficacy (bacteria) - Anaplasma244
Anorexia243
Scratching235
Lack of efficacy (endoparasite) - roundworm NOS221
Weight loss220
Lack of efficacy (endoparasite) - tapeworm213

Breeds named in reports

Dog (unknown)2,096
Retriever - Labrador1,549
Poodle (unspecified)1,026
Crossbred Canine/dog984
Retriever - Golden969
Shepherd Dog - Australian537
Chihuahua524
Shepherd Dog - German509
Domestic Shorthair473
Shih Tzu463
Terrier - Yorkshire404
Pit Bull369
Beagle280
Maltese256
Terrier (unspecified)252

Reported outcomes

Outcome Unknown5,935
Recovered/Normal4,655
Ongoing2,710
Died228
Euthanized147
Recovered with Sequela6

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