Pet Recall Facts

Ingredients / Levothyroxine

Levothyroxine: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

3,445Total reports
3,244Dog reports
29Cat reports

FDA-approved products with this ingredient (Green Book)

All approved products with this ingredient, for any species.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

19981
19991
20013
20037
20065
20076
20083
20099
20107
201136
2012365
2013307
2014211
2015165
2016272
2017281
2018259
2019172
2020176
2021155
2022122
2023159
2024283
2025315
2026125

Species named in reports

Dog3,244
Human93
Not given70
Cat29
Horse9

Signs reported after Levothyroxine

Vomiting491
Lethargy (see also Central nervous system depression in Neurological)490
Diarrhoea340
Emesis315
Lack of efficacy - NOS263
Weight loss227
Other abnormal test result NOS219
Elevated alanine aminotransferase (ALT)200
Seizure NOS198
Anorexia196
Overdose189
Death by euthanasia188
Panting185
Polydipsia180
Elevated serum alkaline phosphatase (SAP)167
Polyuria152
Decreased appetite143
Not eating123
Elevated thyroxine (T4)109
Behavioural disorder NOS105
Ataxia104
Elevated blood urea nitrogen (BUN)103
Abnormal radiograph finding91
Low thyroxine (T4)90
Itching89

Breeds named in reports

Retriever - Labrador511
Dog (unknown)317
Retriever - Golden309
Crossbred Canine/dog197
Beagle136
Boxer (German Boxer)116
Shepherd Dog - German98
Mixed (Dog)85
Chihuahua83
Poodle (unspecified)71
Spitz - German Pomeranian62
Terrier (unspecified)60
Shih Tzu59
Pit Bull59
Terrier - Yorkshire56

Reported outcomes

Recovered/Normal1,096
Outcome Unknown941
Ongoing940
Euthanized186
Died100
Recovered with Sequela90

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