Pet Recall Facts

Ingredients / Isoflurane

Isoflurane: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

5,174Total reports
2,720Dog reports
2,008Cat reports

FDA-approved products with this ingredient (Green Book)

All approved products with this ingredient, for any species.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

19901
19911
19921
19936
199410
199523
199621
199724
199831
199927
200022
200125
200221
200323
200420
200519
200644
200738
200838
200944
201088
201181
2012183
2013266
2014208
2015247
2016239
2017241
2018203
2019201
2020228
2021234
2022366
2023465
2024639
2025576
2026270

Species named in reports

Dog2,720
Cat2,008
Human89
Other72
Not given64
Horse47
Rabbit44
Rat20

Signs reported after Isoflurane

Death773
Lethargy (see also Central nervous system depression in Neurological)566
Vomiting426
Cardiac arrest415
Bradycardia398
INEFFECTIVE, ANESTHESIA364
Anorexia340
Not eating319
Behavioural disorder NOS284
Lack of efficacy - NOS263
Other abnormal test result NOS242
Apnoea241
Death by euthanasia237
Hypothermia237
Diarrhoea223
Fever209
Tachycardia201
Hypotension200
Ataxia195
Dilated pupils186
Vocalisation181
Recovery prolonged180
Hyperthermia175
Seizure NOS169
Weight loss159

Breeds named in reports

Domestic Shorthair1,085
Dog (unknown)442
Retriever - Labrador321
Cat (unknown)266
Crossbred Canine/dog162
Domestic Longhair145
Retriever - Golden120
Chihuahua120
Poodle (unspecified)105
Mixed (Dog)98
Domestic (unspecified)96
Shepherd Dog - German92
Domestic Mediumhair85
Shih Tzu84
Cat (other)71

Reported outcomes

Recovered/Normal1,742
Ongoing1,106
Died831
Outcome Unknown754
Euthanized229
Recovered with Sequela46

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