Pet Recall Facts

Ingredients / Doxycycline

Doxycycline: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

4,404Total reports
3,952Dog reports
253Cat reports

FDA-approved products with this ingredient (Green Book)

All approved products with this ingredient, for any species.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

19972
199815
199915
20003
20011
20029
20036
200425
200519
200622
200718
200837
200923
201013
201123
2012139
2013144
201487
201593
2016159
2017280
2018361
2019318
2020375
2021337
2022309
2023352
2024464
2025511
2026243

Species named in reports

Dog3,952
Cat253
Not given176
Horse15
Human8

Signs reported after Doxycycline

Lack of efficacy (endoparasite) - heartworm1,232
Lethargy (see also Central nervous system depression in Neurological)703
Vomiting603
Other abnormal test result NOS369
Death by euthanasia333
Anorexia313
Elevated alanine aminotransferase (ALT)291
Diarrhoea275
Lack of efficacy - NOS272
Death242
Cough238
Anaemia NOS236
Fever233
Weight loss227
Leucocytosis NOS218
Abnormal radiograph finding217
Not eating207
Decreased appetite198
Thrombocytopenia183
Seizure NOS175
Neutrophilia171
Elevated serum alkaline phosphatase (SAP)165
Ataxia155
Panting150
Elevated total bilirubin135

Breeds named in reports

Dog (unknown)665
Retriever - Labrador536
Crossbred Canine/dog271
Shepherd Dog - German212
Beagle190
Chihuahua189
Terrier - Bull - American Pit183
Retriever - Golden149
Domestic Shorthair140
Terrier (unspecified)118
Shepherd Dog - Australian110
Poodle (unspecified)105
Pit Bull102
Boxer (German Boxer)101
Siberian Husky89

Reported outcomes

Ongoing2,023
Outcome Unknown913
Recovered/Normal579
Euthanized325
Died266
Recovered with Sequela26

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