Pet Recall Facts

Ingredients / Cyclosporine

Cyclosporine: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

23,196Total reports
15,116Dog reports
3,026Cat reports

FDA-approved products with this ingredient (Green Book)

All approved products with this ingredient, for any species.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

19952
199636
199727
199811
199918
20007
200124
200214
200311
20041,041
20051,267
2006944
2007912
20081,267
20091,211
20101,146
20111,090
20122,128
20131,960
20141,497
20151,114
20161,079
2017752
2018712
2019682
2020648
2021597
2022661
2023615
2024686
2025761
2026274

Species named in reports

Dog15,116
Not given4,966
Cat3,026
Human86
Other2

Signs reported after Cyclosporine

Vomiting5,184
Diarrhoea2,863
Anorexia1,465
Depression1,355
Pruritus1,158
Emesis1,077
Lethargy (see also Central nervous system depression in Neurological)1,071
Other abnormal test result NOS933
Weight loss886
Elevated serum alkaline phosphatase (SAP)729
Lack of efficacy - NOS687
Elevated alanine aminotransferase (ALT)652
INEFFECTIVE, ATOPY CONTROL651
Product problem628
Containers, Leaking623
Death by euthanasia622
Gingival hyperplasia610
Uncoded sign541
UNPALATABLE528
Polydipsia511
Underfilling, Container484
Tubes, Damaged474
Polyuria459
Behavioural disorder NOS456
Tubes, Leaking444

Breeds named in reports

Domestic Shorthair1,581
Crossbred Canine/dog1,389
Retriever - Labrador1,067
Shih Tzu1,030
Dog (unknown)912
Terrier - West Highland White806
Retriever - Golden569
Spaniel - Cocker American544
Terrier - Yorkshire495
Shepherd Dog - German482
Pug475
Bichon Frise458
Dachshund (unspecified)405
Cat (unknown)373
Domestic (unspecified)366

Reported outcomes

Recovered/Normal3,599
Ongoing2,470
Outcome Unknown2,172
Died584
Euthanized371
Recovered with Sequela127

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