Pet Recall Facts

Ingredients / Butorphanol

Butorphanol: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

7,711Total reports
4,375Dog reports
2,339Cat reports

FDA-approved products with this ingredient (Green Book)

All approved products with this ingredient, for any species.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

19872
19881
19895
19908
19914
19928
199312
19949
199532
199627
199746
199842
199946
200053
200186
200298
2003121
2004135
200586
200661
200763
200864
200981
2010146
2011123
2012211
2013324
2014211
2015231
2016349
2017352
2018340
2019399
2020354
2021383
2022493
2023743
2024806
2025827
2026328

Species named in reports

Dog4,375
Cat2,339
Not given608
Horse299
Other28
Human15
Rabbit6
Cattle4

Signs reported after Butorphanol

Death888
Lethargy (see also Central nervous system depression in Neurological)802
Lack of efficacy - NOS708
Vomiting685
Anorexia483
Diarrhoea443
Bradycardia436
Death by euthanasia390
Cardiac arrest386
Not eating368
Fever332
Seizure NOS323
Behavioural disorder NOS321
Ataxia277
Tachycardia275
Injection site swelling273
Vocalisation264
INEFFECTIVE, SEDATION261
Other abnormal test result NOS250
Elevated alanine aminotransferase (ALT)245
Decreased appetite243
Panting236
Pain NOS217
Hypersalivation216
Weight loss215

Breeds named in reports

Domestic Shorthair1,096
Dog (unknown)823
Retriever - Labrador503
Domestic (unspecified)295
Cat (unknown)276
Crossbred Canine/dog253
Domestic Longhair171
Chihuahua170
Shepherd Dog - German169
Retriever - Golden158
Terrier - Bull - American Pit157
Poodle (unspecified)122
Domestic Mediumhair120
Cat (other)111
Boxer (German Boxer)107

Reported outcomes

Recovered/Normal2,424
Ongoing1,603
Died1,016
Outcome Unknown958
Euthanized371
Recovered with Sequela25

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